【摘要】 目的　评价紫杉醇联合铂类药物治疗非小细胞肺癌的客观疗效及毒副反应。方法　采用紫杉醇注射液联合顺铂或卡铂 ,每 3周为一疗程。所有病人均接受 3个周期以上化疗。结果　 47例病人均可评价疗效 ,有 2 1例病人达到部分缓解 ,有效率为 45 %。中位生存期为 9个月 ,1年生存率为 48%。主要毒副反应为消化道反应、骨髓抑制、肝功能损害等。结论　紫杉醇联合铂类方案是一种对晚期非小细胞肺癌有效的治疗方案 ,毒副反应较小。更多还原

【Abstract】 Objective To evaluate the efficacy and side-effects of paclitaxel combined with cisplatin(DDP) or carboplatin(CBP) in the treatment of non-small cell lung cancer.Methods Paclitaxel combined with cisplatin or carboplatin was received by all the forty-seven patients for three cycles at least.The schedule was repeated every three weeks.Results All the forty-seven patients were evaluable for efficacy.21patients got partial response with rate of 45%.The median survival duration was 9 months and 1-year survival rate was 48%.The main toxicities included digestive tract reaction,myelosuppression and liver function damage.Conclusions Paclitaxel plus DDP or CBP is an effective regiment for advanced NSCLC with tolerable toxicity.更多还原