【摘要】 建立一日法口服乙酰唑胺(ACZ)负荷脑血流显像技术并探讨其临床价值。对 30 名缺血性脑血管病患者在一日内行静息显像和口服乙酰唑胺负荷显像。观察负荷前后脑血管反应性和比较静息显像、负荷显像和CT 检查三者的阳性率。结果是大脑皮质对乙酰唑胺的反应可分为四种类型;CT、静息显像和负荷检查的阳性率分别为 23.3%、26.7%、86.7%。负荷显像阳性率高于单纯静息显像(p<0.05)和 CT 检查(p<0.01)。结论是一日法口服乙酰唑胺负荷显像省时并且经济,可提高缺血性脑血管疾病的诊断率,并反映血管储备能力,值得推广。更多还原

【Abstract】 To develop a technique of one-day protocol of cerebral blood flow imaging with acetazolamide (ACZ) tablet stress and to discuss its clinic value, 99m Tc-ECD SPECT data of regional cerebral blood flow (rCBF) study before and after taking ACZ (2g, oral) were collected in one day on 30 patients diagnosed as ischemic cerebralvascular disease. The responses of cerebralvascula before and after stress were observed and the positive rates of rest, stress test and CT examination were compared. The results show that the responses of rCBF to ACZ can be devided into four patterns. The positive rate of CT, rest test and combined test is 23.3%, 26.7%, 86.7% respectively. The positive rate of combined test is higher than that of rest test (p<0.05) and CT (p<0.01). It is concluded that the one-day protocol ACZ tablet test is time-saving and economic, because it can improve positive rate in cerebral ischemia and provide the information of cerebrovascular reserve capacity.更多还原