【摘要】 目的　了解怀远县钩端螺旋体病 (钩体病 )流行现状及流行趋势。方法　用随机抽样的方法确定调查点及调查对象 ,血清标本用显微镜凝集试验检测并与国家标准 1 5群 1 5株对照确定血清群 ,对动物肾标本接种培养鉴定血清群后进行统计分析。结果　全县总感染率达 4 .37% ,感染血清群主要为黄疸出血群 ,占 97.5 6 % ,平均抗体滴度较高 ,为 1∶ 337.79,年龄性别差异无统计学意义 ;但是县内不同河系分布有所不同 ,涡河以南感染率 (9.80 % )高于涡河以北 (0 .4 9% ) (χ2 =1 7.32 ,P<0 .0 1 ) ;农作物种植种类不同也有明显差异 ,水稻种植区感染率 (1 0 .0 6 % )明显高于非水稻种植区 (1 .98% ) (χ2 =1 5 .4 6 ,P<0 .0 1 ) ,黑线姬鼠为我县黄疸出血群钩体主要的动物宿主 ,感染率为 38.4 6 %。结论　怀远县钩体疫源地类型已由既往的经济疫源地向自然疫源地过渡 ,为混合型疫源地 ,流行形式与稻田型一致 ,以黄疸出血群为主 ,黑线姬鼠为主要动物宿主 ,并从血清学及病原学方面证实了“南黄北移”现象的存在 ,为怀远县乃至整个淮北地区钩体病的预防与控制提供了科学依据更多还原

【Abstract】 Objective In order to understand the epidemic status and tendency of leptospirosis in Huaiyuan county of Anhui province.Methods The subjects were selected by random sampling.Collected sera were detected by MAT and serum groups were confirmed referring to national criterion of 15 groups of leptospirosis.Animal kidney samples were cultured and serum groups were appraised,and then all the data were analyzed.Results The total infection rate of the whole county reaches 4.37%.The dominant category of serum group,serogroup icterohaemorrhagiae,accounts for 97.56%,average antibodies titer is up to 1∶337.79.Apodemus agrariun is the main animal host of the jaundice bleeds groups of leptospirosis in Huaiyuan County,and its infection rate is 38.46%.There is no significant difference of age and gender between different groups,but rates vary in different river areas.The infection rate of southern Guo river area(9.80%)is significantly higher than that to the north(0.49%)(χ 2=17.32, P <0.01).The infection rate of rice planting area(10.06%)is significantly higher than that of non rice planting areas(1.98%)(χ 2=15.46, P <0.01).Conclusion The previous economic epidemic source type of leptospirosis in Huaiyuan County has already transferred to the natural epidemic source type and a mixed type of epidemic source is coming into being.The phenomenon of “The south Serogroup Icterohaemorrhagiae is moving to the north” was confirmed with the help of serology and aetiology concordantly.Therefore scientific basis for prevention and control of leptospirosis in Huaiyuan County and even the area of whole Huaibei is now available.更多还原