【摘要】 目的 :探讨胎儿生长受限 (FGR)时孕妇血清 ,脐血中胎盘泌乳素 (HPL)的变化及意义。方法 :采用化学发光法 (CLIA)测定正常足月妊娠 36例 (正常组 )和足月妊娠FGR36例 (FGR组 )孕妇血清 ,脐血中胎盘泌乳素 (HPL)水平。结果 :FGR组孕妇血清、脐血中胎盘泌乳素HPL与正常对照组比较显著下降 (P <0 .0 1 )。结论 :胎盘泌乳素 (HPL)分泌不足可能与FGR发病有关。母血HPL的测定有助于FGR的诊断和治疗。更多还原

【Abstract】 Objective: To investigate the relationship between fetal growth retardation (FGR) and human placental lactogen(HPL). Method: The concentration of HPL were measured in maternal serum, umbilical blood by using CLIA, The samples were collected from 36 term pregnancies with FGR, and 36 normal pregnancies served as control. Result: The concentration of HPL in maternal blood and umbilical blood were lower in FGR group than that in normal group(p<0.01). Conclusion: This study confirms that in sufficiency of HPL might be a pathogenesis of FGR. Detecting the maternal serum levels of HPL may be a value in the diagnosis and treatment of the patients with FGR.更多还原