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核素骨显像诊断肿瘤骨转移的临床价值

Clinical value of radionuclide bone scintigraphy in diagnosis of skeletal metastases in patients with carcinoma

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【作者】 刘长江刘秀芊苏敏杨建肖亚景

【Author】 LIU Chang-jiang, LIU Xiu-qian, SU Min, et al (Department of Nuclear Medicine,Affiliated Hospital to Guangdong Medical College, Guangdong Zhanjiang 524001,China)$$$$

【机构】 广东医学院附属医院同位素科广东医学院附属医院同位素科 广东湛江524001广东湛江524001广东湛江524001

【摘要】 目的 :分析各类肿瘤骨转移的特点和规律 ,探讨核素骨显像诊断肿瘤骨转移的临床价值。方法 :对 4 6 2例肿瘤患者静脉注射99m Tc -MDP 1110MBq行SPECT全身骨显像 ,并对结果分析。结果 :①肿瘤骨转移阳性结果 :肺癌阳性率 4 4.9% ,乳腺癌阳性率 33.3% ,鼻咽癌阳性率 5 6 .0 % ,前列腺癌阳性率 6 2 .5 % ,消化道肿瘤阳性率 2 4 .5 % ,其他肿瘤阳性率 2 1.4 %。②肿瘤转移部位以脊柱、肋骨、骨盆最为多见。③肿瘤转移灶骨显像多为“热”区病灶。④肿瘤转移率与病程有关。结论 :核素骨显像对肿瘤的早期诊断、疾病分期、治疗方案的选择、预后评估有重要的价值。

【Abstract】 Objective:To investigate the clinical value of radionuclide bone scintigraphy in diagnosis of skeletal metastases in patients with carcinoma. Methods:462 patients with carcinoma were injected intravenously 99m Tc-MDP 1110MBq and performed the whole body imaging.Results:①The positive rate in patients with lung cancer, breast cancer, nasopharyngeal carcinoma, prostate cancer, gastrointestinal carcinoma and otehers was 44.9%, 33.3%, 56.0%, 62.5, 24.5% and 21.4% respectively. ②Frequent sites for metastatic bone scintigraphy lesions were the spine, pelvic bone and ribs. ③Most of bone metastases showed "hot" spots. ④The rate of metastatas was related with course of carcinoma. Conclusion: Radionuclide bone scintigraphy has important clinic values for patients with carcinoma in early diagnosis, malignant tumor staging,treatment and response to therapy.

【关键词】 骨显像骨转移SPECT
【Key words】 Radionuclide bone scintigraphySkeletal metastasesSPECT
  • 【分类号】R730.43
  • 【被引频次】5
  • 【下载频次】60
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