【摘要】 分别以D,L-乳酸(D,L-LA)、L-乳酸(L-LA)为原料,与乙醇酸(GA)通过熔融聚合法进行共聚,在催化剂SnCl2用量0.5％(wt)、反应温度165℃、反应压力70Pa、反应时间10h的条件下直接合成了生物降解的医用纤维材料聚乙醇酸-乳酸(90/10)(PGLA 910)。产品用IR、DSC、X-射线衍射等进行了表征,并与乙交酯开环聚合二步法合成的PGLA910进行了比较。直接熔融聚合产品的结晶度接近于二步法,D,L-PGLA910的结晶度和微晶尺寸比L型的大。直接熔融共聚工艺流程短、简单易行、耗时少、成本低,有利于医用纤维材料PGLA910的规模开发。更多还原

【Abstract】 Respectively using D,L-lactic acid and L-lactic acid as starting material, and via melt polymerization with glycolic acid, poly(glycolic acid-lactic acid) (90/10) (PGLA910) was directly synthesized after 10h’s copolycondensation under 165℃ and 70Pa, and using 0.5 wt% SnCl2 as catalyst. The biodegradable medical fiber material PGLA910 was characterized with FTIR, DSC and X-ray diffraction, and the properties were compared with that of products synthesized via two-step method of glycolide ring-opening polymerization. The crystallity of PGLA910 produced by direct way was near the value of product in two-step method. When all directly synthesized, D.L-PGLA910 had bigger crystal dimension and higher crystallity than L-PGLA910. For shorter and simpler process, less time, and lower cost, the direct melt polymerization had more advantage than the two-step method in the development of medical fiber material PGLA910.更多还原