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CT引导经皮肺活检诊断早期周围型肺癌的价值

The Value of the CT-guided Lung Biopsy through the Skin to Diagnose the Early Peripheral Lung Cancer

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【作者】 吴峰程传虎罗雯霏陈芳许高运金

【Author】 WU Feng,CHENG Chuan-hu,LUO Wen-fei,CHEN Fang-xu,GAO Yun-jin (Huizhou Municipal people’s hospital,Guangdong Huizhou 516002,China)

【机构】 广东省惠州市人民医院呼吸科广东省惠州市中心人民医院放射科广东省惠州市人民医院呼吸科 广东惠州516002广东惠州516001广东惠州516002广东惠州516002

【摘要】 目的 评估CT引导经皮肺活检对早期周围型肺癌的诊断价值。方法  46例周围型肺癌的医学记录被回顾 ,2 0例行纤维支气管镜检查并行刷检和 (或 )活检 ,3 8例行CT引导经皮肺活检 (包括 12例纤支镜检查未见异常者 ) ,9例 (包括 3例CT引导经皮肺活检和 6例纤支镜检查 )因诊断不明确行胸廓切开术 ,所有标本送做细胞学、组织学和微生物学检查。结果 CT引导肺活检病理确诊率 92 .1%( 3 5 3 8例 )显著高于纤支镜检查 10 .0 %( 2 2 0例 ) (P <0 .0 1) ,9例手术全部明确诊断肺癌。CT引导肺活检并发症仅 2例发生少量气胸 ,未做特殊处理 ,发生率 5 .3 %( 2 3 8) ,按肺癌TNM临床分期 :CT引导肺活检确诊肺癌有手术指征为 91.4%( 3 2 3 5例 )而纤支镜确诊 2例均为晚期肺癌。结论 CT引导肺活检是一种安全、并发症低、正确率高和小的侵入性方法 ,并可迅速诊断早期肺癌

【Abstract】 Objective To evaluate the value of the CT-guided lung biopsy through the skin to diagnose the early lung cancer.Methods 46 cases of peripheral lung cancer were reviewed.20 cases took fiberbronchoscope examinations,brush biopsy and/or biopsy.28 cases,including 12 cases of no findings by fiberbronchoscope,took CT-guided lung biopsy through the skin.9 cases,including 3 cases having taken CT-guided lung biopsy and 6 cases having taken fiberbronchoscope examinations,took thoracotomy because of making no definitive diagnoses.All specimens took cytologic,histological and microbiological examinations.Results The pathological definitive diagnosis rate of 92.1% (35/38) by CT-guided lung biopsy is much higher than 10.0 (2/20) by fiberbronchoscope (P<0.01).9 cases operated were all made definitive diagnoses of lung cancer.Only 2 cases of CT-guided lung biopsy had complications.Small pneumothorax set in without any special treatments.Occurrence of complications is 5.3% (2/38).According to the TNM clincal classificaion of lung cancer:91.4% cases made definitive diagnoses of lung cancer by CT-guided lung biopsy had operation indication while 2 cases made definitive diagnoses by fiberbronchoscope were both advanced lung cancer.Conclusions CT-guided lung biopsy is a safe method with low complications,high rate of correction and little invasion.It can make a definitive diagnosis of early lung cancer rapidly.

【基金】 20 0 1年广东省惠州市科技局课题立项项目 (惠市科字〔2 0 0 1〕7号 )
  • 【文献出处】 海南医学 ,Hainan Medical Journal , 编辑部邮箱 ,2004年05期
  • 【分类号】R734.2
  • 【被引频次】3
  • 【下载频次】41
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