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脑脊液β2微球蛋白检测在病毒性脑炎患儿中的临床意义

There is a clinical significance in dectecting the β2-microglobulin level in cerebrospinal fluid in the children patients with viral encephalitis

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【作者】 梁永正史伟梁馨苓刘双信何朝生李增清

【Author】 LIANG Yong-zheng,SHI Wei,LIANG Xin-ling,LIU Shuang-xin,HE Chao-sheng,LI Zheng-qing (Guangdong Provincial People Hospital Department of Nephrology,Guangzhou 510080,China)

【机构】 广东省人民医院肾内科广东省人民医院肾内科 广东广州510080广东广州510080广东广州510080

【摘要】 目的 为了解脑脊液 β2 微球蛋白 (CSFβ2 -M)在病毒性脑炎患儿中的临床意义。方法 用放射免疫法(RIA)测定 3 0例病毒性脑炎患儿CSFβ2 -M。结果 表明患儿早期CSFβ2 -M较对照组明显升高 ,与白细胞计数、蛋白质、糖、乳酸脱氢酶含量低度相关 ,但无统计学意义 ,与病情轻重程度无关 ,与病程长短呈显著正相关。结论 提示CSFβ2 -M可作为诊断病毒脑的一种参考指标 ,亦可作为估计病程的依据之一。

【Abstract】 Objective We want to know the clinical significance of dectecting the β 2-microglobulin level in cerebrospinal fluid in the children patients with viral encephalitis.Methods We dectected β 2-microglobulin levels of 30 children patients with viral encephalitis in cerebrospinal fluid with radio-immunity assay.Results The results implied that the level of β 2-microglobulin in cerebrospinal fluid in the early period of disease is obviously increased compared to the control,and is lowly correlated to the white blood cell count,level of protein,glucos and lactate dehydrogenase in cerebrospinal fluid,but the correlation is no statistical significance,the results also implied that the level of β 2-microglobulin is not correlated to the severity of the diseases and is significantly positive correlated to the continuing time of the disease course.Conclusions Our study suggested that the level of β 2-microglobulin in cerebrospinal fluid is a referent sign in diagnosising viral encephalitis and is one of evidences to estimate the disease course.

  • 【文献出处】 海南医学 ,Hainan Medical Journal , 编辑部邮箱 ,2004年04期
  • 【分类号】R725.1
  • 【下载频次】35
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