【摘要】 设计了可检测十二指肠胃返流的光纤传感器 ,该传感器由 4 70nm的信号光、5 95nm参考光和光纤束构成 ,主要检测十二指肠返流物中的胆红素在 4 70nm与 5 95nm的吸光度 ,本文还对影响传感器检测的因素 ,诸如波长、pH、胃液中悬浮颗粒造成的散射作用以及其他的因素 ,做了详细评价 传感器可以达到10mg/dl优良的动态响应范围 ,离体实验结果表明 ,该传感器可以作为临床动态检测手段更多还原

【Abstract】 A fiber-optic sensor for monitoring of duodenogastric reflux is fabricated. The sensing system, based on the principle of double-beam compensation, includes two diodes for light sources, blue at 470 nm as signal light and yellow at the wavelength of 595 nm as reference one, and a Y model fiber optic bundle for transmitting light. The sensor performs on detection of spectrophotometric absorption of bilirubin always present in entero-gastric reflux at 470 nm and 595 nm. A general evaluation of the sensor about factors affecting its detection is discussed in detail: Wavelength choice, pH, scattering effect resulting from gastric precipitates and others. The sensor shows a good excellent performance with a dynamic linear range of up to 10 mg/dl. The in-vitro experiment shows it can be used in clinical analysis of DGR.更多还原