【摘要】 目的　讨论妊娠期糖尿病 (GDM)和孕期糖耐量受损 (GIGT)对母儿的影响。方法　对 74 3例孕妇于孕 2 4～ 2 8周进行口服 5 0g葡萄糖筛查 (5 0gGCT) ,血糖≥ 7 8mmol L者进一步行口服 75g葡萄糖耐量试验 (OGTT) ,对 5 0gGCT正常者具有高危因素者于 32～ 34周重复 5 0gGCT。结果　 5 0gGCT阳性率为 6 73% ,GDM及GIGT检出率分别为 3 90 %和 3 2 3%。GDM及GIGT中妊娠高血压综合征 (PIH)、巨大胎儿、低血糖、新生儿窒息、剖宫产的发生率均较高。结论　对所有孕妇进行 5 0g葡萄糖筛查 ,及早确诊GDM及GIGT ,可降低母儿的发病率 ;同时提供了一次检出Ⅱ型糖尿病 (NIDDM)高危人群的良机。更多还原

【Abstract】 Objective To study the influence of gestational diabetes mellitus(GDM) and gestational impaired glucose tolerance(GIGT) to pregnant women and their babies.Method 743 pregnant women with gestational age of 24～28 weeks were screened by 50g glucose challenge test(50g GCT),75g oral glucose tolerance test(OGTT) was performed for those with serum glucose concentration≥7.8mmol/L,while repeated 50g GCT was performed for the high-risk pregnant women with normal result in initial GCT during 32～34 gestation weeks.Result The positive rate of 50g GCT was 6.73%,the detection rates of GDM and GIGT were 3.90% and 3.23% respectively.Higher incidence of pregnancy-induced hypertension syndrome(PIH),fetal macrosomia,neonatal hypoglycemia,asphyxia and proportion of cesarean section were found in patients with GDM or GIGT.Conclusion All pregnant women should be screened by 50g GCT,so as to lower the incidence of maternal and fetal complications.更多还原