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肝硬化患者血清和腹水中酸性α-醋酸萘酯酶的含量

Measurements of Acid Alpha Naphthyl Acetate Esterase Levels in Serum and Ascites of Liver Cirrhosis Patients

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【作者】 王燕周力张永宏张维陈玉梅

【Author】 WANG Yan 1, ZHOU Li 1, ZHANG Yong-hong 1, ZHANG Wei 2, CHEN Yu-mei 1 (1.Department of Digestive Internal Medicine, The Affiliated Hospital of Guiyang Medical College, Guiyang 550004, China; 2.Department of Hematology, The Affiliated Hospital of Guiyang Medical College, Guiyang 550004, China)

【机构】 贵阳医学院附院消化内科贵阳医学院附院血液内科贵阳医学院附院消化内科 贵州贵阳550004贵州贵阳550004贵州贵阳550004

【摘要】 目的 :探讨肝硬化患者血清、腹水酸性α 醋酸萘酯酶 (ANAE)的含量与肝硬化肝功能Child pugh分级的关系。方法 :比色法测定肝硬化患者血清、腹水ANAE含量。结果 :肝硬化患者血清、腹水ANAE含量较对照组明显降低 ,其中肝硬化肝功能ChildB级以后血清、腹水ANAE含量下降明显。血清、腹水ANAE含量相关性显著。结论 :肝硬化患者血清、腹水ANAE含量 ,在一定程度上反映肝脏功能损害

【Abstract】 Objective: To investigate the relationship between acid alpha naphthyl acetate esterase levels (ANAE) in serum and ascitic fluid of liver cirrhosis patients and Child’s grading of their liver function. Methods: α-ANAE levels in serum and ascite were measured with colorimetric assay. Results: α-ANAE levels in serum and ascite of liver cirrhosis patients were significantly lower than those of healthy controls (P<0.01). They correlated with the Child’s grading of liver function well. Conclusion: α-ANAE levels in serum and ascite of liver cirrhosis patients markedly decline and correlate with parameter of liver function. They may be useful in assessing the degree of liver damage.

  • 【文献出处】 贵阳医学院学报 ,Journal of Guiyang Medical College , 编辑部邮箱 ,2004年03期
  • 【分类号】R575.204
  • 【被引频次】1
  • 【下载频次】39
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