【摘要】 目的　研究脑梗塞患者血小板计数(PLT)、血小板平均体积(MPV)、血小板分布宽度(PDW)变化以及临床意义。方法　选择98例脑梗塞患者用全自动血细胞分析仪测定急性期和恢复期MPV、PLT、PDW。80例健康人作为正常对照组。结果　急性期MPV、PDW分别为10.96±1.32、12.31±2.27,较对照组以及恢复期显著升高(P<0.05);血小板数目为148.74±42.62,显著低于对照组与恢复期(P<0.05),而恢复期与对照组无差异。脑梗塞患者的梗塞面积越大,MPV、PDW越高,大面积组较小面积组、小面积组较腔隙性梗塞组患者的MPV、PDW均有显著性差异(P<0.05)。结论　动态检测MPV、PDW、PLT等血小板参数可作为临床上估计梗塞范围, 监测病情和判断预后的一项指标, 对观察药物疗效亦有帮助,值得临床应用。更多还原

【Abstract】 Objective To study the changes and clinical significance of platelet number (PLT), meanplatelet volume (MPV ), and platelet distribution width (PDW )in patients with cerebral infarction(CI).Methods Ninety-eight patients with cerebral infarction were randomly selected and 80 health peopleas control. PLT , MPV and PDW were examined .Results MPV and PDW in acute cerebral infarction(<72h)were significantly higher than control group and recovery phase. PLT in acute cerebral infarction wassignificantly lower than control group and recovery phase. In big cerebral infarction , MPV and PDW werehigher than small infarction and lacunar infarction(P<0.05). Conclusion These results show that anelevation in mean platelet volume and reduction in platelet count are features of cerebral infarction.It is possible that these changes may precede the occurrence of cerebral infarction. In addition todetect the MVP and PDW is helpful to evaluate the extent and prognosis of cerebral infarction.更多还原