人群水痘—带状疱疹病毒流行率及发病状况分析

【摘要】 为了解本辖区现阶段健康人群水痘 -带状疱疹病毒 (VZV)流行情况 ,采用酶联免疫吸附实验 (ELISA)分别对本地以及外来人员共 40 7名 1～ 50岁健康人群VZV的血清流行病学情况进行检测 ,同时根据 2 0 0 2始纳入国家传染病管理信息系统报告的天河区水痘发病状况进行统计分析。结果显示 :人群中血清抗VZV -IgG阳性率平均为 61 7% ,年龄别流行率 1～ 2岁、3～ 6岁、7～ 1 2岁、1 3～ 1 9岁、2 0～ 2 9岁、30～ 39岁、40～ 50岁组分别为 1 4 1 %、2 4 3 %、62 0 %、85 7%、95 2 %、92 9%、1 0 0 % ,说明血清年龄别流行率以1～ 6岁组最低 ,以后随年龄增长而上升。同时对天河区 2 0 0 2～ 2 0 0 3年收到报告的 1 883例水痘病例分析表明 ,1 0岁以下儿童的发病占总病例的 79 1 % ,与所检测的人群VZV流行率相一致 ,表明婴儿、幼儿、学前班儿童、小学低年级学生为高度易感人群 ,是水痘疫苗的主要免疫对象更多还原

【Abstract】 In order to know sero-prevalence of varicell-zoster virus(VZV)in healthy people, a whole varicella virus antibody (ELISA kit) was used to investigate the sera prevalence rate of VZV in 407 local and outland health population of 1～50years old and analyze the varicella cases from infection report system The results showed that The seropsitive rate of VZV antibody was 61 7% Age-specific prevalence of anti-VZVin 1～2,3～6,7～12,13～19,20～29,30～39and 40～50 age groups were 14 1%,24 3%,62 0%,85 7%,95 2%,92 9%and 100% respectively that means age-specific prevalence rate is lowest in 1～6 age groups and increase along with age Analyze the 1 883 varicella cases showed that incidence cases under 10 years old children is account for proportion of 79 1% and it was accord with the age-specific prevalence of anti-VZV above Infant and beginglow school children in immunity level to VZVwere the main immunifactioners of varicella vaccine更多还原