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傅里叶变换红外光谱法用于体表无创性检测乳腺肿瘤的研究

Application of Fourier Transform Infrared Spectroscopy to Non-invasive Detection of Breast Tumor in vivo and in situ

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【作者】 李庆波徐智徐怡庄张元福张能维王立新孙学军张莉王凡杨丽敏赵莹任予刘智翁诗甫周维金吴瑾光

【Author】 LI Qing-Bo1, XU Zhi2, XU Yi-Zhuang 1*, ZHANG Yuan-Fu1, ZHANG Neng-Wei2 WANG Li-Xin2, SUN Xue-Jun3, ZHANG Li1, WANG Fan1, YANG Li-Min1, ZHAO Ying4 REN Yu3, LIU Zhi1, WENG Shi-Fu1, ZHOU Wei-Jin1, WU Jin-Guang1 (1. The State Key Laboratory of Rare Earth Materials Chemistry and Applications, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China; 2. The Third Hospital, Peking University, Beijing 100083, China; 3. The First Hospital of Xi′an Jiaotong University, Xi′an 710061, China; 4. Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China)

【机构】 北京大学化学与分子工程学院北京大学第三医院西安交通大学第一医院中国科学院化学研究所北京大学化学与分子工程学院 稀土材料化学及应用国家重点实验室北京100871北京100083稀土材料化学及应用国家重点实验室西安710061北京100080北京100871

【Abstract】 The non-invasive detection of breast tumor in vivo and in situ was first investigated by FTIR fiber optics technique. The experiment result indicates that there are significant differences between the spectra of skin outside breast tumor and normal breast tissues in the peak position and relative intensity. The in vivo FTIR spectroscopy can provide the information concerning whether the suspected tissue is cancerous or not. This recent result means that in situ FTIR spectroscopic method with fiber optics can be developed as a non-invasive, rapid and in vivo technique for early breast tumor detection.

【基金】 国家重点基础研究发展规划项目(批准号:2002CCA01900);国家自然科学基金(批准号:30371604,50203001,20171004);教育部博士学科点基金资助.
  • 【文献出处】 高等学校化学学报 ,Chemical Research In Chinese Universities , 编辑部邮箱 ,2004年11期
  • 【分类号】R737.9
  • 【被引频次】18
  • 【下载频次】266
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