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扑热息痛片剂药品的近红外光谱法非破坏定量分析

Nondestructive Quantitative Analysis of Paracetamol Tablet Medicines by NIR Spectroscopy

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【作者】 窦英邱芳萍刘培义任玉秋任玉林

【Author】 DOU Ying1, QIU Fang-Ping2, LIU Pei-Yi1, REN Yu-Qiu3, REN Yu-Lin 1 * (1. College of Chemistry, Jilin University, Changchun 130023, China; 2. College of Bioengineering, Changchun University of Technology, Changchun 130012, China; 3. Baicheng Medical College, Baicheng 137000, China)

【机构】 吉林大学化学学院长春工业大学生物工程学院白城医学院吉林大学化学学院 长春130023长春130012长春130023白城137000长春130023

【Abstract】 The application of artificial neural network(ANN) and near-infrared spectroscopy for pharmaceutical nondestructive quantitative analysis of Paracetamol was investigated. The artificial neural network patterns of Paracetamol tablet medicines, powder medicines, first derivative spectra and second derivative spectra were established, and they were compared each other. The uncertain specimens were predicted. The parameters affecting ANN were discussed. A new network evaluation criterion, i.e., the degree of approximation, was employed, and the predicted results were reliable.

【基金】 吉林省科技厅基础研究项目 (批准号 :2 0 0 10 50 3 )资助
  • 【文献出处】 高等学校化学学报 ,Chemical Research In Chinese Universities , 编辑部邮箱 ,2004年01期
  • 【分类号】O657.3
  • 【被引频次】29
  • 【下载频次】229
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