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三重-比导数分光光度法及其应用研究
Triple ratio derivative spectrophotometry and its application
【摘要】 提出了可以应用于三元混合物同时测定的三重 比导数分光光度法,阐述了三重 比导数分光光度法的基本原理,研究了三重 比导数分光光度法在三元复方制剂增效联磺片中磺胺甲口恶唑(SMZ)、磺胺嘧啶(SD)、甲氧苄啶(TMP)的同时测定。试验结果表明,增效联磺片中SMZ、SD、TMP的回收率分别为102 1%(RSD=2.7%,n=20)、100.5%(RSD=1.8%,n=20)、101.2%(RSD=4 3%,n=20)。
【Abstract】 The triple ratio derivative spectrophotometry was used for simultaneous determination of a ternary mixture by the method was discussed. The simultaneous determination of three components in pharmaceutical containing sulfamethoxazole, sulfadiazine and trimethoprim by the method was studied and the results were satisfactory. The average recoveries of sulfamethoxazole, sulfadiazine and trimethoprim were 102.1% (RSD=2.7%, n=20), 100.5%(RSD=1.8%, n=20), and 101.2%(RSD=4.3%, n=20), respectively.
【关键词】 三重比导数分光光度法;
原理;
磺胺甲口恶唑;
磺胺嘧啶;
甲氧苄啶;
【Key words】 Triple ratio derivative spectrophotometry; Sulfamethoxazole; Sulfadiazine; Trimethoprim;
【Key words】 Triple ratio derivative spectrophotometry; Sulfamethoxazole; Sulfadiazine; Trimethoprim;
- 【文献出处】 分析试验室 ,Analytical Laboratory , 编辑部邮箱 ,2004年10期
- 【分类号】O657.32
- 【被引频次】8
- 【下载频次】92