【摘要】 20 0 4年诺贝尔化学奖颁给了 3位发现细胞是如何摧毁蛋白质的科学家———阿龙·切哈诺沃、阿夫拉姆·赫什科和欧文·罗斯。本文详细介绍了他们的发现 ,重点介绍了泛素调节下蛋白质降解所需要的各种物质及其机理。更多还原

【Abstract】 The Nobel Prize in Chemistry 2004 was awarded to three scientists: Aaron Ciechanover, Avram Hershko and Irwin Rose. They succeeded in showing how proteins are destroyed in cells. The article introduce their discovery, especially the substances wanted in the course of the ubiquitin-mediated protein degradation and the mechanism.更多还原