【摘要】 基于发光试剂通过电价键将铁氰化钾固定在阴离子交换树脂上 ,可直接对待测物马来酸麦角新碱进行传感 ,从而建立测定药物马来酸麦角新碱的传感器新方法。其线性范围为 5× 10 -3 ～ 1mg/L ,线性方程为ΔI =10 6 .4 5C +17.10 (R2 =0 .998) ,检出限达到 2 .6 μg/L。对 0 .0 1和 0 .1mg/L的马来酸麦角新碱进行10次测定 ,它们的相对标准偏差 (RSD)分别为 2 .1%、2 .4 %。此传感器的稳定性良好 ,可连续使用 2 0 0次以上。此法已成功地用于马来酸麦角新碱注射液含量的测定以及尿样中马来酸麦角新碱含量的检测更多还原

【Abstract】 A novel flow injection chemiluminescence (CL) sensor for the determination of ergonovine maleate has been developed. Hexacyanoferrate(Ⅲ) was immobilized electrostatically on an anion-exchange resin column and was eluted from the column using sodium phosphate solution as eluent. The sensor responds linearly to ergonovine maleate concentration in the range of 5.0×10 -3 to 1.0 mg /L with a detection limit (3σ) of 2 6 μg/L. The sensor is stable for determinations 200 times and has been successfully applied to the determination of ergonovine maleate in injections and urine samples.更多还原