【摘要】 目的 :探讨急性播散性脑脊髓炎 (ADEM)脑部MRI及临床表现、病程、预后间的关系。方法 :回顾性分析 43例的MRI表现及临床资料 ,按病灶大小、数目分组 ,分析病灶大小、数目与临床表现、病程及预后间的关系。结果 :双侧脑室周围及额、颞、顶、枕白质区见多发、不对称长T1长T2 信号灶 ,部分T1WI为等信号。 18例见环形强化 ,3例轻度至中度占位效应。病灶大小与临床分级组间差异有显著性意义 (P <0 .0 5 ) ;病灶大小与病程、预后无明显相关性 ;病灶数目与临床分级、病程均无明显相关性。结论 :综合分析ADEM的脑部MRI表现 ,可在一定程度上为临床诊断、病情评估、治疗监测及评估预后提供依据。更多还原

【Abstract】 Objective:To study the correlations between MRI findings and clinical features,course of disease and prognosis in patients with acute disseminated encephalomyelitis (ADEM).Methods:A retrospective study was conducted on 43 patients with ADEM,in which the correlations were evaluated by SPSS software between the size and number of lesions on MRI and clinical features,course of disease and prognosis.Results:Multiple and asymmetrical white matter lesions were revealed in the frontal,parietal,occipital,temporal,and periventricular areas.The lesions showed long T 1 and T 2 signals.Peripheral ring-type enhancement was observed in 18 cases and mass effect in 3 cases.There was a significant correlation between the size of lesions in ADEM and clinical grading (P<0.05).No correlations were found between the size of lesions and course of disease and prognosis,and between the number of lesions and course of disease and clinical grading (P> 0.05). Conclusion:Analyzing comprehensively the MRI findings in ADEM may provide to a certain extent,evidences for clinical diagnosis,evaluation of clinical grading and prognosis.更多还原