【摘要】 目的:探讨整肠生预防早期新生儿黄疸的临床疗效。方法:92例新生儿随机分为干预组和对照组。干预组出生0.5h开奶后给予整肠生0.5g/次,3次/d,连用5d。两组每天测胆红素1次。结果:干预组总胆红素≥12.9mg/dl的占11%,对照组为33%(χ2=6.29,P<0.025),黄疸峰值干预组(8.1±4.9)mg/dl,对照组(9.9±3.4)mg/dl(t=2.061,P<0.025);黄疸持续时间干预组(6.4±3.5)d,对照组(8.1±4.1)d(t=2.129,P<0.025)。结论:早期新生儿口服整肠生有助于胆红素代谢排出,减少新生儿胆红素异常增高,缩短黄疸持续时间,避免新生儿由于胆红素过高所致损害。更多还原

【Abstract】 Objective: To explore the clinical effects of Zhengchangsheng on treatment of jaundice in early neonates. Methods: Ninety-two neonates were divided randomly into two groups: intervention group and control group. The neonates of intervention group were given Zhengchangsheng 0.5 g three times a day for 5 days. The total serum bilirubin (TB) of all the neonates was measured 0.5 hours after birth, once a day for 5 days. Results: The incidence of hyperbilirubinemia (TB≥12.9 mg/dl) in intervention group was 11%, and that in the control group was 33% (t = 2.061, P < 0.025). The mean peak value of TB in intervention group was (8.1±4.9) mg/dl and the mean peak value in control group was (9.9±3.4) mg/dl (t = 2.06l, P < 0.025). Duration of jaundice in intervention group was 6.4±3.5 days, and that in the control group was 8.1±4.1 days (t = 2.129, P < 0.025). Conclusions: Zhengchangsheng could accelerate the metabolism of bilirubin, prevent the abnormal increase of serum bilirubin, shorten the duration of jaundice and avoid the injury caused by hyperbilirubinemia in early neonates.更多还原