【摘要】 目的　探讨尿毒症患者与正常人的肠道细菌能否利用肌酐。方法　将肌酐作为唯一能量来源加入尿毒症患者与正常人的肠道细菌 (n =10 ) ,再加入指示剂Tetrazoliumviolet,溶液显紫色为阳性。肠道细菌加入含有肌酐的营养肉汤中 ,测定培养前后肌酐值。结果　尿毒症患者肠道细菌溶液呈紫色 ,正常人的显淡紫红色 ,吸光值P <0 0 0 1。培养后的肌酐值均有下降 ,肌酐分解值P <0 0 5。结论　尿毒症患者与正常人的肠道细菌均能利用肌酐 ,前者的能力强更多还原

【Abstract】 Objective To explore the ability of intestinal bacteria making use of creatinine in the patients with uremia and healthy subjects. Methods Creatinine, which was energy source only,and tetrazolium violet as indicator were added into intestinal bacteria of the patients with uremia and healthy subjects(n=10). It was positive that solution showed violet. Intestinal bacteria were added in Nutrient Broth medium with creatinine. The concentration of creatinine was measured before and after incubation. Results The solution of intestinal bacteria of the patients with uremia showed violet. The solution of intestinal bacteria of healthy subjects showed bright violet.The concentration of creatinine decreased after incubation in both groups. Conclusions The intestinal bacteria of uremic patients and healthy subjects had the ability to make use of creatinine. The former was stronger than the latter.更多还原