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知母多糖对家兔血糖的影响

Effect of anemam on rabbit blood glucose

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【作者】 黄彩云谢世荣黄胜英

【Author】 HUANG Cai-yun,XIE Shi-rong,HUANG Sheng-ying (College of Medicine,Dalian University,Dalian 116622, China)

【机构】 大连大学医学院大连大学医学院 辽宁大连116622辽宁大连116622辽宁大连116622

【摘要】 [目的]〗研究知母多糖(Anemam,AM)对家兔血糖的影响.[方法]制备家兔高血糖模型,用不同剂量组的AM和D860后,测定对照组、AM组、D860组的血糖.[结果]AM1次灌胃2mg/kg,20mg/kg可显著降低四氧嘧啶引起的家兔血糖升高;AM1次灌胃20mg/kg对正常家兔血糖无明显影响,200mg/kg可降低正常家兔血糖.[结论]AM与D860同样具有实验性降低血糖作用.

【Abstract】 [Objective] To research the effect of anemam (AM) on rabbit blood glucose. [Methods]Chemical drug-induced diabetes rabbit models were used to investigate the effect of AM on rabbit blood glucose .The rabbits were given AM at the different doses and D860. The rabbit blood glucose of the control group, AM group and D860 group was measured. [Results] AM 2 mg/kg and 20 mg/kg ig could significantly reduce the blood glucose of the alloxan-induced diabetes rabbits. AM 20 mg/kg ig had an insignificant effect on the normal rabbit blood glucose. AM 200 mg/kg ig could reduce blood glucose of normal rabbits. [Conclusion]AM has the similar experimental effect of reducing blood glucose to that of D860 .

【关键词】 知母多糖甲苯磺丁脲血糖家兔
【Key words】 anemam(AM)tolbutamideblood glucoserabbit.
  • 【文献出处】 大连大学学报 ,Journal of Dalian University , 编辑部邮箱 ,2004年04期
  • 【分类号】R285
  • 【被引频次】66
  • 【下载频次】587
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