【摘要】 对丙酮酸脱氢酶复合酶系的组成、功能及特性进行了简要的综述 丙酸酸脱氢酶系是1个定位在线粒体中更多还原

【Abstract】 The structure and functional properties of pyruvate dehydrogenase complex （PDHC） have been reviewed briefly.PDHC is a mitochondrial multienzyme complex including pyruvate dehydrogenase（E₁）,dihydrolipoamide acetyltransferase（E₂）,dihydrolipoamide dehydrogenase（E₃）,pyruvate dehydrogenase,pyruvate dehydrogenase phosphatase,five cofactor and protein X.Pyruvate dehydrogenase complex converts pyruvate to aceryl-CoA that is subatrate for the citric acid cycle.Lactic acidosis can arise from the deficiency of PDHC.更多还原