【摘要】 以姜酮为前体得到的烯醇硅醚 ,在三氯化铋的催化下 ,与芳香醛发生Mukaiyamaaldol缩合 ,脱去苄基得到 3种新颖的具有 β 羟基酮结构的姜醇类似物 .控制缩合反应的温度 ,还得到一种苯并环庚酮和一种苯并环戊烷 .这些化合物及其中间产物的结构均用1 HNMR ,IR ,MS及元素分析进行了表征 .更多还原

【Abstract】 Zingerone is used as precursor and converted to its kinetic O-silylated derivative, and then coupled with various aromatic aldehyde in the Mukaiyama aldol reaction. The products are treated with debenzylation and three analogues of gingerols are obtained, which are β-hydroxyl ketone structure. One benzosuberone and one benzocyclopentane are synthesized when controlling the condensation reaction temperature. Their structures are confirmed by elemental analysis, IR, 1HNMR and MS spectra.更多还原