【摘要】 运用膜片钳技术对急性分离的大鼠背根神经节神经元细胞上的电压依赖性钾离子通道进行了研究。在细胞贴附式记录模式下 ,去极化可以激活一个电导为 2 0pS的钾离子单通道电流 ,分析了其单通道的特性 ,提出了其动力学的模型。对于了解大鼠背根神经节神经元细胞的电活动机制具有重要的意义更多还原

【Abstract】 Using the patch clamp recording technique, we studied voltage dependance K + single channel in acute dissociated neurons from the rat dorsal root ganglion neurons (DRG). In cell attached mode, depolarization could activate a single K + channel currents which conductance was 20pS. We analysed the characteristics of single K + channel, and constructed the kinetics model. What we have done is very significant for knowing about current signal mechaniums of DRG.更多还原