【摘要】 目的 :观察无症状的中老年吸烟者和不吸烟者的肺气肿损害情况。方法 :选择 31名吸烟者和 2 9名从不吸烟者。采用高分辨CT(HRCT)在吸气状态下用 1 .5mm切片厚度和 3cm切片间隔完成检查。由 2名X线技术员 ,通过视觉评估肺气肿损害情况。结果 :肺气肿改变出现在吸烟组中 1 5名 (4 8.4 % ) ,而不吸烟组只有 1名 (3.4 % ) ,差异有显著性 (P <0 .0 0 5 )。结论 :HRCT检查肺气肿损害在无症状吸烟组中是明显的 ,出现临床症状之前 ,可以发现早期肺气肿损害更多还原

【Abstract】 Objective:To study the occurrence of emphysematous lesion in symptom free smokers of about 50 to 60 years of age and non smokers.Methods:A randomized study was conducted in 31 smokers and 29 non smokers with high resolution computed tomography(HRCT).HRCT was performed at full inspiration with a 1.5 mm slice thickness and a 3 cm inter slice distance.Evaluation was made by two radiologists and emphysematous lesions were scored visually.Results:Emphysematous lesions were demonstrated in 15 of the 31 smokers but in only one non smoker.Emphysematous lesions were evident in 48.4% of the healthy symptom free smokers.The difference was significant( P <0.005).Conclusions:HRCT may reveal early emphysematous lesion in smokers before they have any clinical symptoms.更多还原