【摘要】 丹皮酚与相应的酰氯反应得到 5个新的丹皮酚酯 ,其结构通过光谱法确证。它们的体外抗肿瘤活性通过MTT法和集落形成法进行了评价。初步的体外生物试验结果表明 ,5 硝基 2 呋喃甲酸的丹皮酚酯对人肿瘤细胞有一定抑制作用 ,其结果和临床上常用的抗肿瘤药 5 Fu相近更多还原

【Abstract】 Five new paeonol esters were prepared by reacting paeonol with the corresponding acid chloride. Their in vitro antitumor activity against human cancer cell lines were evaluated by MTT assay and colony formation assay. Preliminary biological activity showed that 5 nitro 2 furoic acid paeonol ester 5 is effective against human cancer cells更多还原