【摘要】 目的:观察螺内酯对冠心病慢性心力衰竭的临床疗效。方法:冠心病慢性心力衰竭患者80例,随机分为治疗组40例,对照组40例,对照组选用利尿剂氢氯噻嗪及氨苯喋啶、血管紧张素转换酶(ACE)抑制剂卡托普利、β-受体拮抗剂倍他乐克,洋地黄制剂地高辛为主要治疗药物。治疗组以螺内酯替代上述氨苯喋啶,其他治疗同对照组,治疗3个月后评判疗效。结果:治疗组总有效率达92.5%,对照组总有效率为75.0%,两组比较有显著性差异(P<0.05)。结论:螺内酯治疗冠心病慢性心力衰竭可明显提高临床疗效。更多还原

【Abstract】 Objective To observe the effect of spironolactone treatment in patients with chronic heart failure of coronary heart disease. Methods 80 patients with chronic heart failure of coronary heart disease were randomly divided into therapy group (40 cases) and control group (40 cases).The patients in control group used mainly diuretil, angiotensin converting enzyme inhibitors( ACEI) , β - adrenoceptor blocking drugs and digitalis. On the basis of the above treatment, patients in therapy group used spironolactone instead of triamterene. Clinical effects were evaluated after three- month treatment. Results The total effectiveness of the therapy group was 92.5% , and the total effectiveness of the control group was 75.0% . There was distinctive difference between the two groups (P<0.05). Conclusion Spironolactone can improve the clinical therapy effect obviously.更多还原