【摘要】 目的 :研究洋芹素、槲皮素 3 ,3’ 二甲醚和槲皮万寿菊素 3 ,6 二甲醚 7 吡喃葡萄糖苷的体外抗氧化作用。方法 :大鼠脑、肾和肝匀浆自氧化和经Fe2 + VitC诱导产生丙二醛 (MDA) ,TBA比色法检测这三种化合物的抗氧化活性。结果 :洋芹素、槲皮素 3 ,3’ 二甲醚和槲皮万寿菊素 3 ,6 二甲醛 7 吡喃葡萄糖苷浓度在 6.2 5～ 5 0 μmol/L能明显降低大鼠脑、肾和肝匀浆MDA含量。结论 :洋芹素、槲皮素 3 ,3’ 二甲醚和槲皮万寿菊素 3 ,6 二甲醚 7 吡喃葡萄糖苷体外具有抗氧化活性。更多还原

【Abstract】 Objective: To study the antioxidant action of apigenin?quercetin-3,3’-dimethyl etherhe and quercetagetin-3,6-dimethyl ether-7-o-glucoside in vitro. Methods: MDA level induced by Fe2+-VitC or autooxidation in rat brain, kidney and liver homogenates were determined by TBA colorimetric analysis. Results: apigenin, quercetin 3,3’ dimethyl etherhe and quercetagetin 3,6-dimethyl ether-7-o-glucoside could reduce MDA formation in rat brain, kidney and liver homogenates. Conclusion: apigenin, quercetin-3,3’-dimethyl etherhe and quercetagetin-3,6-dimethyl ether 7 o glucoside from Seriphidium terrae-albae (Krasch) Poljak have distinct antioxidant action.更多还原