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沙棘籽油对肝损伤小鼠免疫功能的影响

Influence of seed oil of hippophae rhamnoides L. (SOHR) on immune effect in mice of hepatocirrhosis

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【作者】 覃红程体娟佟婉红任雅

【Author】 Qin Hong, Chen Tijuan, Tong Wanhong, Ren Ya (Department of Pharmacologe, Lanzhou Medical College, Lanzhou 730000)

【机构】 兰州医学院药理教研室兰州医学院药理教研室 兰州730000兰州730000兰州730000

【摘要】 目的 :研究沙棘籽油的对肝损伤小鼠免疫功能的影响。方法 :采用D 半乳糖胺造成小鼠肝损伤模型 ,观察沙棘籽油对正常及肝损伤小鼠免疫功能的影响。结果 :沙棘籽油能使正常和D GaIN致肝损伤小鼠腹腔巨噬细胞吞噬功能、血清溶菌酶活性、脾淋巴细胞转化和IL 2活性增强。结论 :沙棘籽油能增强小鼠的免疫功能。

【Abstract】 Objective: To observe the Influence of seed oil of hippophae rhamnoides L. (SOHR) on immune effect in mice of hepatocirrhosis. Methods: A model of hepatocirrhosis induced by D galactose (D GaIN) were used to investigate the influence SOHR on immunity in mice. Results: SOHR could enhance the phagocyte activity of peritoneal macrophages, increase the content of serum lysozyme, and increase the lymphocyte transformation and the activity of IL 2 in normal and hepatocirrhosis mice. Conclusion: SOHR had immunopotentiation.

  • 【文献出处】 中药药理与临床 ,Pharmacology and Clinics of Chinese Materia Medica , 编辑部邮箱 ,2003年01期
  • 【分类号】R285.5
  • 【被引频次】8
  • 【下载频次】230
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