【摘要】 目的　为了掌握西安市婴儿麻疹疫苗 (以下简称MV)基础免疫接种情况 ,以进一步提高免疫成功率。方法　在西安市城区和郊区随机抽查 5 7名 0岁组健康婴儿 ,采用酶联免疫吸附法 (ELISA)测定血清麻疹IgG抗体水平。结果　免疫前MV阳性率为 2 8 0 7% ,GMT 1∶4;免疫后MV阳性率为 98 2 5 % ,GMT 1∶1666;免疫前后阳性率、抗体平均滴度经统计分析 ,差异有非常显著性 (P <0 .0 1) ;对MV免疫后不同性别、不同地区的抗体阳性率 ,平均滴度进行统计分析 ,差异无显著性 (P >0 0 5 )。结论　婴儿在出生后 8个月 ,母体胎传抗体逐渐衰减 ,致MV阳性率极低 ,只需按现行的免疫程序及时有效地接种MV ,就能获得保护抗体 ,达到控制麻疹发病的目的。同时也说明MV的免疫成功与否不受性别和地区的影响。更多还原

【Abstract】 To master the status of measles vaccine immunity inoculation among infants in Xian, and to improve the success of immunity inoculation. 57 healthy infants were randomly selected from the urban and rural areas of Xian, their blood serum IgG was determined with ELISA method.Positive rate of MV before inoculation was 28.07%, GMT was 1:4; after inoculation, the positive rate of MV was 98.25%, GMT was 1:1 666. There was significant difference in positive rate and antibody before and after inoculation according to the statistic analysis (P<0.01). There was no significant difference in gender and area after MV inoculation (P>0.05) .[Conclusion] After born for 8 months, the infants have a decrease of inherited antibody that lead to a very low MV positive rate. They may obtain antibody merely by receiving MV inoculation, therefore MV can be controlled. At the meantime, the result also showed that the success of immunity inoculation couldn’t be affected by gender and area difference.更多还原