【摘要】 目的 :评价中药提取物水苏糖对亚临床肝性脑病 (SHE)的治疗作用。方法 :5 8例SHE患者随机分为试验组 30例及对照组 2 8例 ,试验组给予水苏糖 10～ 6 0mL·d-1,对照组给予乳果糖 10～ 6 0mL·d-1,均为 po ,tid根据个体差异调整剂量使患者保持每日 2～ 3次软便 ,疗程均为 4周。服药前后行数字连接试验 (NCT)和诱发电位检查。结果 :2组治疗后诱发电位各波潜伏期及NCT均较治疗前明显缩短 (P <0 .0 5 ) ,2组间各波潜伏期及NCT无差异 (P >0 .0 5 )。结论 :水苏糖作为治疗SHE的药物 ,与乳果糖一样有很好的疗效。更多还原

【Abstract】 Objective:To evaluate the therapeutic effect of stachyose in treatment of subclinical hepatic encephalopaty(SHE).Methods:58 patients with SHE were randomly divided into the test group ( n= 30) and the control group ( n= 28) to receive stachyose 10～60mL·d -1 , po ,tid and lactulose 10～60mL·d -1 , po ,tid,respectively,for 4 weeks.The dose of two group were adjusted to achieve 2 or 3 semiformed stools during treatment.The latency of evoked potential and number connected tests (NCT) were performed in both groups before and after administration of drug.Results:The latency of evoked potential and NCT were significantly shortened in both groups in comparison with those before administration of drug ( P <0.05) and no difference existed between groups.Conclusion:Stachose is as effective as lactulose in treatment of SHE.更多还原