【摘要】 目的 :制备氟康唑眼药膜。方法 :研究制剂的制备工艺 ,建立质量标准 ,采用紫外分光光度法测定制剂中氟康唑的含量 ,进行眼药膜体外释放特性的研究。结果 :制剂制备工艺简单 ,质量便于控制 ,眼药膜中氟康唑的回收率为 (99.2 1± 0 .30 ) % ;氟康唑眼药膜在生理氯化钠溶液中 4h释放 76 .7% ,T50 为 2 0min ,Td 为 53min。结论 :氟康唑眼药膜可以满足临床需要更多还原

【Abstract】 Objective:To prepare the fluconazole eye film.Methods:Fluconazole eye film was prepared,its quality standard was established,and its release characteristics was studied.Results:The quality of fluconazole eye film thus prepared was stable.The determination method had a recovery of (99.21±0.30)%,and drug liberation from the film was 76.7% in 4h, T 50 =20min, T d=53min.Conclusion:A preparation procedure for fluconazole eye film and a method for determining its content are provided by the authors.更多还原