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黄蜜浆与质子泵抑制剂对上消化道出血的临床研究

Study on treatment of upper digestive tract hemorrhage by Huangmi starch(黄蜜浆) and proton pump inhibitor

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【作者】 林平连铭峰张强张烈湖杨建民

【Author】 LIN Ping 1,LIAN Mingfeng 2,ZHANG Qiang 1,ZHANG Liehu 1,YANG Jianmin 2.1.The First Hospital of Longyan,Longyan 364000, Fujian,China; 2.The First Aid Center of Longyan, Longyan 364000, Fujian, China

【机构】 福建省龙岩市第一医院福建省龙岩市急救中心福建省龙岩市急救中心 福建龙岩364000福建龙岩364000福建龙岩364000

【摘要】 目的 :探讨中西药合用对上消化道出血的临床治疗价值及应用规律。方法 :将 1 30例小、中量上消化道出血患者随机分为单用黄蜜浆治疗 (黄蜜浆 )组 4 2例、单用质子泵抑制剂治疗 (质子泵 )组 4 2例及黄蜜浆和质子泵抑制剂联合治疗 (黄蜜泵 )组 4 6例 ,比较 3组的治疗效果和止血时间。结果 :黄蜜泵组痊愈率 (87.0 % )高于质子泵组 (6 9.0 % ,P<0 .0 5 ) ,止血时间〔包括黑便转黄时间和便潜血转阴时间 ,分别为 (36 .5± 1 0 .2 ) h和(2 .5± 0 .9) d〕也明显优于质子泵组〔分别为 (81 .4± 2 5 .5 ) h和 (5 .2± 1 .9) d,P均 <0 .0 1〕和黄蜜浆组〔分别为(5 2 .3± 1 5 .6 ) h和 (3.9± 1 .2 ) d,P均 <0 .0 1〕。结论 :黄蜜浆与质子泵抑制剂联合运用治疗上消化道出血可缩短止血时间 ,提高治疗效果 ,有协同作用

【Abstract】 Objective: To investigate the therapeutic value and application regularity on treatment of upper digestive tract hemorrhage with traditional Chinese and western medicine Huangmi starch and proton pump inhibitor.Methods:One hundred and thirty patients with upper digestive tract hemorrhage were randomly divided into three groups,42 patients were treated with Huangmi starch, 42 patients were treated with proton pump inhibitor,and 46 patients were treated combined with Huangmi starch and proton pump inhibitor .The therapeutic efficacy and hemostatic time were observed and compared in three groups. Results: The fully recovery rate in patients treated by Huangmi starch and proton pump inhibitor were highter than treated by proton pump inhibitor(87 0% vs.69 0%, P <0 05),hemostatic time in patients treated by Huangmi starch and proton pump inhibitor were better than only Huangmi starch or proton pump inhibitor groups 〔the time of tarry stood turned yellow and stood occult blood disappeared: (36 5±10 2) h,(2 5±0 9) d vs.(52 3±15 6)h,(3 9±1 2)d,and (81 4±25 5)h,(5 2±1 9)d,all P <0 01〕.Conclusion:Treatment of upper digestive tract hemorrhage combine with Huangmi starch and proton pump inhibitor can shorten hemostatic time,increase therapeutic efficacy. Huangmi starch and proton pump inhibitor have synergistic action.

【基金】 福建省教育厅科研计划项目 ( JB 0 0 195 )
  • 【文献出处】 中国中西医结合急救杂志 ,Integrated Traditional Chinese and Western Medicine In Practice of Critical Care Medicine , 编辑部邮箱 ,2003年03期
  • 【分类号】R573.2
  • 【被引频次】4
  • 【下载频次】44
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