【摘要】 目的 :研究活脑灵加高压氧治疗血管性痴呆的临床疗效。方法 :选择 4 0例血管性痴呆患者 ,随机分为两组 (各 2 0例 )。对照组患者只采用内科常规治疗 ,治疗组患者则加用活脑灵和高压氧治疗。采用简易智力状态检查表 (MMSE)和长谷川痴呆量表 (HDS)对药物疗效进行评价。结果 :治疗组和对照组改善症状的总有效率分别为 92 .85 %和 4 3.5 6 % (P<0 .0 1) ;提高生活能力总有效率分别为 73.5 7%和 6 5 .0 3%。治疗组治疗前后MMSE为 (14 .8± 3.5 )分和 (2 2 .9± 4 .3)分 (P<0 .0 1) ,HDS为 (14 .2± 5 .8)分和 (2 2 .6± 6 .5 )分 (P<0 .0 1)对照组治疗前后 MMSE和 HDS虽有改善 ,但不显著 (P均 >0 .0 5 )。治疗组与对照组治疗后比较 MMSE和 HDS均有显著性差异 (P<0 .0 1和 P<0 .0 5 )。结论 :活脑灵加高压氧治疗血管性痴呆的临床疗效确切、安全 ,是治疗血管性痴呆的措施之一。更多还原

【Abstract】 Objective:To investigate the clinical curative effect of fonzylane and high oxygen pressure in treatment of vascular dementia. Methods:Forty cases of patients with vascular dementia were randomly divided into treatment group(20 cases) and control group(20 cases). The control group was treated with routine therapy,the treatment group was add fonzylane and high oxygen pressure.MMSE and HDS were used to evaluate the therapeutic efficacy.Results:The total effective rates of improving symptoms were 92 85% and 43 56% ( P <0 01),and the total effective rates of enhancing life ability were 73 57% and 65 03% respectively in treatment group and control group.In treatment group,MMSE was (14 8±3 5) scores before treatment and (22 9±4 3) scores after treatment( P <0 01),HDS was (14 2±5 8)scores before treatment and (22 6±6 5) scores after treatment( P <0 01).In control group,MMSE and HDS were improved after treatment, but the difference was not significant (both P >0 05).MMSE and HDS had significantly difference after treatment in treatment group compared to control group( P <0 01 and P <0 05).Conclusion:fonzylane and high oxygen pressure is efficacious and safe for the treatment of vascular dementia .It’s one of measures to treat vascular dementia.更多还原