【摘要】 目的 :探讨硬膜外麻醉复合全身麻醉方法对气管拔管应激反应的预防作用。方法 :2 2例气管插管全麻下手术患者 ,随机分为对照组和硬膜外组 ,每组各 11例。两组麻醉前用药、麻醉诱导和维持方法相同 ,硬膜外组气管拔管期间复合应用硬膜外麻醉。分别在麻醉前、拔管前、拔管后 1min、2 min、5 min、10 min各采集动脉血标本 ,测定血浆儿茶酚胺等浓度 ,并做血气分析 ,计录各时点的血流动力学参数。结果 :两组气管拔管期间血浆儿茶酚胺等浓度均明显增高 ,两组比较对照组高于硬膜外组。结论 :气管拔管期间复合硬膜外麻醉能减轻气管拔管引起的应激反应。更多还原

【Abstract】 Objective:To investigate the effect of epidural block combined with general anesthesia on the concentrations catecholamine (CA), coticol and carbohydrate metabolism during tracheal extubation.Method:Twenty-two patients scheduled for general anesthesia with tracheal intubation were randomly divided into two groups:control group and epidural group.Epidural anesthesia was given to epidural group during tracheal extubation in addition to common same general anesthesia in two groups. The change of hemodynamic,arterial plasma concentration of CA,AⅡ, cotisol, blood sugar,lactic acid were measured before anesthesia,before intubation and 1,2,5,10 min after tracheal extubation respectively.Result:There were significantly increased leveld of CA,AⅡ, cotisol, blood sugar,lactic acid during tracheal extubation in two groups ,but the levels of CA were higher markedly in control group than in epidural group(P<0.05 or P<0.01) .The change of homodynamic were more stable in epidural group than in control group.Conclusion:epidural anesthesia during tracheal extubation may attenuate stress response during tracheal extubation.更多还原