【摘要】 目的 :观察 5例严重急性呼吸综合征 (SARS)患者胸部影像学动态演变与应用糖皮质激素治疗的关系。方法 :对 5例 SARS患者在其他用药方案相同的情况下 ,给予甲基氢化泼尼松治疗 ,动态观察胸部影像学的演变。结果 :5例患者在同一剂量甲基氢化泼尼松 (16 0 m g/ d)应用情况下 ,胸部影像学资料显示病灶呈进行性发展 (进展高峰出现于发病的第 4～ 12 d) ,并在 4 8h内有吸收消散。结论 :糖皮质激素在 SARS患者治疗过程中 ,对 X线胸片病变的发展似乎无干预作用 ,提示 SARS病程可能存在自限性。更多还原

【Abstract】 Objective: To investigate the relationship between corticosteroid therapy and kinetic changes in chest Xray in five patients with severe acute respiratory syndrome (SARS). Methods:With the identical underlying therapy (levofloxacin or ceftriaxone and macrolide), intravenous methylprednisolone was given at 80 mg twice a day in five patients, and its effect on the development of chest radiogram was observed. Results: Chest Xrays radiogram showed significant changes until peak stage (412 days) with the same doses of methylprednisolone, but it was dissolved consistently afterwards. Conclusion: It is appeared that corticosteroid therapy has no marked effect on the development of chest radiogram in patients with SARS. It might indicate there is selflimited in course of SARS.更多还原