【摘要】 1日龄肉鸡感染 J亚群禽白血病病毒 (AL V- J)以及共感染禽网状内皮增生症病毒 (REV)后 ,肉鸡生长发育明显受阻 ,体重增重明显下降 (P<0 .0 5 ) ,法氏囊、胸腺明显萎缩 (P<0 .0 5 ) ,在用新城疫疫苗免疫后 ,感染组血清中新城疫抗体效价显著低于对照组 (P<0 .0 5 ) ;在 AL V- J和 REV共感染后 ,这种抑制作用更为明显 (P<0 .0 1 )。AL V- J单独感染后 ,鸡对传染性法氏囊病病毒 (IBDV)弱毒疫苗免疫后的抗体反应与对照组没有明显差别 ,但 AL V- J与 REV的共感染可明显延缓鸡对 IBDV弱毒疫苗免疫的抗体反应更多还原

【Abstract】 When 1 day old broilers were infected with avian leukosis virus of subgroup J(ALV J) strain NX0101,the body weight was significantly reduced,atrophy of the bursa and thymus was detected,and antibody reaction to Newcastle disease virus vaccine was inhibited,while compared to the control birds(P<0 05).Such phenomena were even more serious when birds were co infected with ALV J strain NX0101 and reticuloendotheliosis virus(REV) strain SD9901 as compared to controls(P<0 01) or to birds infected with ALV J alone(P<0 05).ALV J infection alone gave no influence on reaction to IBDV vaccination in birds,but co infection of ALV J and REV apparently delayed antibody reactions to IBDV.This is the first report to demonstrate the immunosuppression of ALV J infection on broilers especially when co infcted with REV.更多还原