【摘要】 [目的]探讨腹膜转运率增高及其相关因素。[方法]选择我院46例行持续性不卧床式腹膜透析(CAPD)的患者行腹膜平衡试验(PET)。根据PET结果评价腹膜转运功能,将其分为高转运、高于平均、低于平均和低转运四型。血容量由Xitron-4200生物电阻仪检测并用病人的干体质量作标化处理[Vecv,mb(L·kg-1)]。[结果]PET结果显示5例低转运、13例低于平均、20例高于平均和8例高转运。其4 h肌酐D/Pcr值与病人血压呈显著正相关关系(r=0.35,P<0.01),同时4 h肌酐D/Pcr值与Vecv,mb也呈显著正相关关系(r=0.42,P<0.001).高转运者血压与Vecv,mb均显著高于低转运者(P<0.01),血压与Vecv,mb也呈显著正相关关系(r=0.45,P<0.001)。[结论]腹膜通透性增高的病人有高血压和血容量过多的临床表现,这与他们的临床预后差可能有一定关系。更多还原

【Abstract】 [Objective] To investigate the relationship between increased peritoneal transport rate and its risk factors. [Methods] 46 CAPD patients were included in the present study. A peritoneal equilibration test was done in each patient. The extracellular fluid volume (ECV) was measured using a Xitron-4200 bioimpedance assessment device and was normalized by patients dry body mass [Vecv, mb,/ (L .kg-1) ]. [Results] There were significant correlations between D/P creatinine and mean blood pressure (r=0. 35, P<0.01), between D/P creatinine and Vecv, mb(r = 0.42, P < 0. 001) and between Vecv, mb and mean blood pressure (r = 0. 45, P < 0. 001). [Conclusion] The results suggest that increased peritoneal transport rate is associated with fluid overload and increased blood pressure. These changes may contribute to the worse clinical outcome in patients with high peritoneal transport rate.更多还原