【摘要】 目的 :评价重症急性胰腺炎 (SAP)早期手术的治疗效果。方法 :回顾性分析 14 7例重症急性胰腺炎 (SAP)的治疗情况 ,其中 38例伴有单个或多个重要脏器功能障碍 (SAP -Ⅱ )。将早期手术治疗的SAP -Ⅱ 2 3例与早期非手术治疗的SAP -Ⅱ 15例在病死率及并发症发生率等方面进行对比分析。结果 :早期手术组中病死率和并发症发生率分别为 30 .4 3% (7/ 2 3)和 34.78% (8/ 2 3) ,早期非手术组中病死率和并发症发生率分别为 6 6 .6 7% (10 / 15 )和 4 6 .6 7% (7/ 15 ) ,两组比较早期手术组的病死率明显低于早期非手术组 (P <0 .0 5 ) ,而并发症发生率差别不大。结论 :早期手术对一些严重的重症急性胰腺炎 (SAP -Ⅱ )患者是必需的。在SAP早期保守治疗期间出现 1个或多个重要脏器功能障碍时应进行手术治疗以降低病死率。更多还原

【Abstract】 Objective:To evaluate the curative effects of early surgery for patients with severe acute pancreatitis (SAP).Methods:147 SAP patients were analyzed retrospectively.38 out of 147 patients with SAP presented single or multiple organ dysfuction (SAP-Ⅱ) in early stage of SAP.Among them 23 patients underwent early operation,and they were studied and compared with 15 patients treated non-surgically in early stage of SAP.Results:The mortality in the early operation group was 30.43%(7/23),compared with 66.67%(10/15) of those not receiving operation in early stage.Statistic analysis showed that there was significant difference between them.Conclusion:Early operation is necessary for some severe cases.In early stage of SAP surgery should be performed when patients present single or multiple organ dysfunction under routine conservative management in order to decrease the mortality of SAP.更多还原