【摘要】 目的 :为了解药品片剂释放药量的情况 ,本文对国内 6家药厂生产的卡马西平片 (0 .1g× 10 0 )进行了溶出速率研究。方法 :测定方法参照《中国药典》2 0 0 0年版二部溶出度第二测定方法进行。结果 :6家药厂生产的卡马西平片 (0 .1g× 10 0 )的溶出速率相差较大 ,有的在 30min内即全部达到其溶出度规定 ,而有的要到 6 0min才能达到溶出度规定 ;并且 ,即使同一药厂生产的卡马西平片 ,其 6片在 2 0min内的溶出速率也相差较大。结论 :国内 6家药厂生产的卡马西片 (0 .1g× 10 0 )的溶出速率相差较大。更多还原

【Abstract】 Objective:To acquaint with situation of drug quantity of dissolving out of pharmacy tablet,we investigated the speed of dissolving out situation of domestic carbamazepine tablets(0.1×100) produced by six pharmaceutical factories.Methods:Refer to testing second methods of degree of dissolving out of pharmacy tablet in 《Pharmacopeia of China》2000 year edition,second portion.Results:Speed of dissolving out of the carbamazepine tablets(0.1g×100)produced by six pharmaceutical factories are greatly different among them,even in same one.Some accord with stipulation of degree of dissolving out of the drug within 30 minutes;while some accord with stipulation of degree of dissolving out of the drug within 60 minutes.Conclusion:speed of dissolving out of the domestic carbamazepine tablets(0.1g×100) produced by six pharmaceutical factories is quite different.更多还原