【摘要】 目的 :研究血尿酸水平与高脂血症的关系。方法 :比较高脂血症病人 (10 3例 )和正常血脂对照者 (10 9例 )间血尿酸水平的差别 ;简单相关和多元逐步回归分析血尿酸水平和血脂间的线性相关关系 ;Logistic回归分析血尿酸对高脂血症发病的影响程度。结果 :高脂血症组血尿酸水平 [(382 .4± 10 0 .3) μmol/L]高于正常血脂对照组 [(35 1.7± 88.9) μmol/L](P <0 .0 5 ) ;血尿酸水平与TG、ApoB间呈正相关 (P <0 .0 5 ,P <0 .0 5 ) ,与HDL间呈负相关 (P <0 .0 5 ) ;调整年龄、性别、BMI、SBP、DBP、PP、MAP、Glu后 ,血尿酸水平与高脂血症的发病间无相关性 (P >0 .0 5 )。结论 :血尿酸水平在高脂血症病人增加 ,与血脂密切相关 ,但不是高脂血症发病的独立危险因素。更多还原

【Abstract】 Objective:To study the relationship between serum uric acid level and hyperlipidemia.Methods:The serum uric acid level between hyperlipidemia group (103 cases) and control group (109 cases) was compared.The correlation of serum uric acid level and hyperlipidemia was analysed using multiple stepwise regression model.The logistic regression analysis was used to investigate the association of serum uric acid level with the incidence of hyperlipidemia.Results:The serum uric acid level in hyperlipidemia group[(382.4±100.3)μmol/L] was significantly higher than in control group[(351.7±88.9)μmol/L]( P <0.05). The serum uric acid level was obviously positively correlated with TG and ApoB ( P <0.05, P <0.05).There was notably negative correlation between serum uric acid level and HDL ( P <0.05).The serum uric acid level was not associated with the incidence of hyperlipidemia after adjusting age,sex,BMI,SBP,DBP,PP,MAP and Glu ( P >0.05).Conclusion:The serum uric acid level increases in the hyperlipidemia patients, and is closely related to blood lipid, but it is not an independent risk factor for hyperlipidemia.更多还原