【摘要】 目的　探讨隐匿性乳腺癌的发病特点、诊断和治疗方法。方法　对经治的 12例隐匿性乳腺癌的临床及病理资料进行回顾性分析。结果　 12例均以腋下肿块为首发症状且均予手术治疗。手术方式为腋下肿块切除术 1例 ,腋下肿块切除加单纯乳房切除 1例 ,乳腺癌根治术 6例 ,改良根治术 4例。 11例获随访 1～ 15年。随访期间行腋下肿块切除和加行单纯乳房切除的 2例分别于术后18个月和 2 2个月死于全身多器官转移 ;1例行乳腺癌根治术者于术后 3年出现腋淋巴结转移而再次手术 ,于再次术后 4年死于肺转移 ;其余患者仍存活 ,其中已生存 3年以上 2例 ,5年以上 2例 ,10年以上 4例。结论　对原因不明的腋下肿块 ,应考虑到隐匿性乳腺癌的可能 ,同时应予切除并送检病理确诊。腋下淋巴结转移癌的组织学结构对肿瘤来源能提供重要线索。一经确诊 ,本病宜选择乳腺癌根治术或改良根治术 ,并予辅助性放疗、化疗。更多还原

【Abstract】 Objective To investigate the characteristic, diagnosis and treatment of occult breast carcinoma(OBC). Methods The clinical data of 12 cases of OBC were analyzed retrospectively.Results All patients showed axillary node enlargement as the first sign and were operated on. The operation included axillary node excision (ANE) in 1 patient, axillary node excision plus simple mastectomy in another one, radical mastectomy in 6, and modified radical mastectomy in the other 4,respectively. Eleven patients (91.7%) were followed up for 1-15 years. During the follow up, 1 patient who underwent axillary node resection and 1 who received ANE plus simple mastectomy died of systemic metastasis,18 and 22 months after operation respectively;another case who subjected to radical mastectomy had axillary lymph node metastasis 3 years after the operation,and was re operated on,but the patient died of lung metastasis 4 years after the reoperation. And the others still survived, in which 2 have lived for over 3 years, 2 over 5 years, and 4 over 10 years. Conclusions For axillary mass which causes are uncertain, the possibility of OBC should be considered.Meanwhile excision and pathological examination are necessary. The metastatic histological structure of the axillary nodes usually provide important clue for the source of tumor. Radical or modified mastectomy is the best treatment,and post operative chemotherapy and/or radiotherapy should be done.更多还原