【摘要】 目的探讨与中青年脑梗死发病关系最为密切的危险因素。方法采用 1∶ 1配比的病例对照研究方法。应用条件 L ogistic回归模型进行单因素及多因素分析。结果多因素分析高血压病史、脑卒中家族史、入院首次舒张压及吸烟史与中青年脑梗死发病关系最为密切 ,OR值分别为 7.4 9(95 % CI 1.5 8～ 35 .5 1)、2 .17(95 % CI 1.32～ 3.5 6 )、1.0 4 (95 %CI 1.0 2～ 1.0 7)及 1.4 7(95 % CI 1.0 3～ 2 .0 9)。结论高血压病、脑卒中家族史及吸烟为中青年脑梗死发病的主要原因。更多还原

【Abstract】 Objective To comprehensively determine the risk factors for cerebral infarction patients aged 18 to 50.Method A pair-matched case-control(1∶1) study was carried out.Data was analyzed with conditional Logistic regression.Results The simple factor analysis showed that the risk factors for cerebral infarction patients aged 18 to 50 was related to hypertension,smoking,alcohol drinking,stroke family history,hypertension family history,systolic and diastolic pressure at admission,contents of blood cholesterol and blood sugar.However,Logistic regression analysis confirmed that occurrence of cerebral infarction was mainly related to patient’s hypertension history(OR=7.49,95%CI 1.58～35.51),stroke family history(OR 2.17,95%CI 1.32~3.56),diastolic pressure on admission(OR 1.04,95%CI 1.02～1.07) and smoking(OR 1.47,95%CI 1.03~2.09).Data showed a statistical significance(P<0.01).Conclusion The results indicated that the most important risk factors for cerebral infarction patients aged 18 to 50 were hypertension,stroke family history and smoking.更多还原