【摘要】 目的　探讨糖尿病 (DM )在不同阶段胃动力紊乱产生的规律 .方法　已确诊糖尿病病人 2 7例 ,糖尿病病人按其有无胃肠症状及其他糖尿病合并症分为两组 ,有胃肠症状同时伴有其他糖尿病合并症组 18例 ,无胃肠症状组 9例 ,同时选 2 0例正常人作对照 .用核素法对糖尿病 (DM )不同阶段胃排空功能的变化进行观察 .结果　有胃肠症状或合并其他脏器并发症的DM病人 12 0min近端胃存留率为 (33.72± 3.6 ) % ,较正常人 (2 3.16± 2 .0 2 ) %(P =0 .0 8)及无胃肠症状DM病人 (17.5 4± 3.0 8) % (P <0 .0 0 5 )增加 ,全胃和近端胃t1/2 分别为 (91.4 6± 9.2 8)min和 (81.87± 8.2 4 )min ,比正常人的 (5 5 .7± 3.6 8)min(P <0 .0 0 5 )和 (5 0 .2 9± 3.5 1)min(P <0 .0 1)明显延长 ;早期无胃肠症状或仅有轻度三多一少症状的DM病人的近端胃排空速率为 (1.10± 0 .12 ) % ,与正常人 (0 .0 8±0 .0 4 ) %相比明显增加 (P <0 .0 5 ) ,12 0min近端胃存留率为 (17.5 4± 3.0 8) % ,与正常人的 (2 3.16± 2 .0 2 ) %比较明显减少 (P =0 .0 6 ) .结论　不同阶段糖尿病患者胃排空功能状态不同 ,DM胃排空异常可能从近端胃开始更多还原

【Abstract】 Objective To study GI motility disorder diabetes mellitus in different stages.Methods 27 cases of DM are divided into 18 cases of symptomatic of GI, 9 cases of asymptomatic of GI, 20 cases of control. We determined gastrical emptying by radiopaque marker.Results Remaining of proximal stomach at end of 120?min were(33.72±3.68)% (vs control, P =0.08),(17.54±3.08)% (vs control, NS, vs symptomatic DM, P <0.005) and(23.16±2.02)% in symptomatic DM, asymptomaric and control group,respectively. It increased in symptomatic DM patients. t 1/2 of total and proximal stomach were (91.46±9.28)min ( P <0.005) and (81.87±8.24)min ( P <0.01) in symptomatic DM and (55.7±3.68)min and (50.29±3.51)min in control. Velocity of proximal stomach in asymptomatic patient was (1.10±0.12)/min, it was significant increased compared with in control (0.82±0.04)/min, P <0.05). Remaining of proximal stomach at the end of 120?min decreased in this group with(17.54±3.08)% ( P =0.06) compared with( 23.16 ±2.02)% in control.Conclusion There were diffierent patterns of gastric content emptying in difierent stages of diabetes:there were normal or accelerated GE of proximal stomach in asymptcroatic patient with DM,and show as delayed, accelerated or normal gastric emptying in symptomatic patient.更多还原