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甲磺酸左氧氟沙星对耐青霉素肺炎链球菌的体外抗菌活性

In vitro antibacterial activity of levofloxacin against penicillin-resistant Streptococcus pneumoniae

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【作者】 于亮李秀春曹文华王靖王梅

【Author】 Yu Liang 1, Li Xiu-chun 1, Cao Wen-Hua 1, Wang Jing 1 and Wang Mei 2 (1 The Affiliated Hospital of Taishan Medical College, Taian 271000; 2 The Centre Hospital of Taian, Taian 271000)

【机构】 泰山医学院附属医院泰安市中心医院 泰安271000泰安271000泰安271000

【摘要】 目的 观察甲磺酸左氧氟沙星对耐青霉素肺炎链球菌 (PRSP)的药敏及疗效。方法 对 6株临床分离的耐青霉素肺炎链球菌 ,采用E test方法 ,测定甲磺酸左氧氟沙星等 6种抗生素的抗菌活性。同时观察甲磺酸左氧氟沙星单药治疗PRSP临床疗效及不良反应。结果  6株PRSP均为低耐药菌株 ,对甲磺酸左氧氟沙星敏感。 6例患者经治疗后 ,5例痊愈 ,1例显效 ,无明显副反应发生。结论 甲磺酸左氧氟沙星可有效治疗耐青霉素肺炎链球菌性肺炎。

【Abstract】 Objective To investigate the antibacterial activity and clinical efficacy of levofloxacin against pencillin-resistant Streptococcus pneumoniae (PRSP). Methods E-test was used to examine the antibacterial activity of levofloxacin and others 5 antibiotics. The side effect and clinical efficacy were estimated after the patients were treated by levofloxacin. Results All 6 patients infected with PRSP were treated successfully by levofloxacin, 6 PRSP strains were susceptible to levofloxacin. Conclusion Levofloxacin could treat the PRSP infection effectively.

  • 【文献出处】 中国抗生素杂志 ,Chinese Journal of Antibiotics , 编辑部邮箱 ,2003年04期
  • 【分类号】R96
  • 【下载频次】60
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