【摘要】 目的　找到解决Hopf分岔从而抑制心律失常的非线性动力学方法。方法　基于心脏电生理活动模型 ,通过所设计的冲蚀滤波器控制分岔指标。结果　通过仿真实验 ,验证该控制方法可以控制分岔幅值以及分岔点的位置和稳定性。结论　针对房颤和异位起搏等疾病的治疗 ,非线性动力学控制实用有效 ,对它的研究在临床上具有重要意义。更多还原

【Abstract】 Objective This paper was the utility of bifurcation control for suppressing abnormal rhythms in nonlinear models of cardiac electro-physiologic activities. Methods Bifurcation controllers that delt with Hopf bifurcation are employed. Washout filter aided feedback controllers were designed to control the location and stability of the bifurcations, as well as the amplitude of the bifurcated solutions. Result An experiment of virtual reality demonstrated the viability and utility of the proposed bifurcation control approach. Conclusion Controlling nonlinear cardiac dynamics might have important clinical implications because arrhythmias in the heart such as fibrillation and ectopic foci threatened life.更多还原