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门静脉高压脾亢术后应用重组人生长激素的临床意义

Application postoperatively of growth hormone in patients with hypersplenism due to portal hypertension

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【作者】 朱为群

【Author】 ZHU Weiqun.Department of General Surgery,Guangzhou Eighth People’s Hospital,Guangdong,510060,China

【机构】 广东广州市第八人民医院普外科 510060

【摘要】 目的 探讨重组人生长激素 (r hGH)对门脉高压症脾亢术后病人的影响。方法 采用随机分组对照研究的方法 ,应用r hGH治疗组 30例 ,对照组 30例。观察两组病人术后疲劳综合征 (POFS)、腹腔感染、切口愈合的情况。结果 治疗组无疲倦 17例 (5 6 6 % ) ,对照组 2例 (6 6 % ) ,两组比较差异有显著意义(P <0 0 1)。治疗组切口甲级愈合 2 7例 (90 % ) ,对照组 18例 (6 0 % ) ,两组比较差异有显著意义 (P <0 0 1)。治疗组和对照组分别有 1例腹腔感染。结论 应用重组人生长激素能减轻和预防POFS ,并且有利于切口的愈合

【Abstract】 Objective To discuss the effects of recombinant human growth hormone on postperative patients with hypersplenism due to portal hypertension.Methods A prospective,randomized and controlled trial was carried out.The experimental group composed of 30 casesand the control group composed of 30 cases.The postoperative fatigue syndrome,infection of abdominal cavity and wound healing were observed.Results The percentage of patients without postoperative fatigue syndrome was 56.6% in experimental group and 6.6% in control group(P<0.01).The first class of wound healing was 90% in experimental group and 60% in control group(P<0.01).There was no significant differences between the two groups with infection of abdominal cavity.Conclusion The recombinant human group hormone are useful in improving postoperative fatigue syndrome and wound healing.

  • 【文献出处】 中国基层医药 ,Chinese Journal of Primary Medicine Pharmacy , 编辑部邮箱 ,2003年10期
  • 【分类号】R657.6
  • 【被引频次】4
  • 【下载频次】27
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