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异丙酚对全麻术后病人恶心、呕吐的影响

Effect of propofol on postoperative nausea and vomiting in the patients undergoing general anesthesia

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【作者】 张中军石碧明任永功

【Author】 ZHANG Zhongjun,SHI Biming,REN Yonggong.Department of Anesthesiology,The People’s Hospital of Shenzhen,The Second Affiliated Hospital of the Medical College in Jinan University,Guangdong,518020,China

【机构】 暨南大学医学院第二附属医院暨南大学医学院第二附属医院 深圳市人民医院麻醉科518020深圳深圳市人民医院麻醉科518020深圳

【摘要】 目的 观察异丙酚预防术后恶心、呕吐的作用。方法  4 7例拟行选择性腹腔镜胆囊切除术病人被随机分为A组 (2 4例 )和B组 (2 3例 )。A组以芬太尼、异丙酚和万可松行麻醉诱导 ;B组以芬太尼、硫喷妥钠和万可松诱导。两组均以吸入异氟醚维持。观察两组病人的麻醉恢复特点和术后 2 4h内恶心、呕吐发生率及应用镇吐药病人数。结果 两组病人术后唤醒时间、完全清醒时间及术后恶心、呕吐的发生率及应用镇吐药病人数相比较 ,A组各值均明显低于B组 (P <0 0 5 )。结论 异丙酚行全身麻醉可有效地预防术后恶心、呕吐 ,并可显著缩短麻醉恢复时间。

【Abstract】 Objective To observe the effect of propofol in preventing postoperative nausea and vomiting.Methods Forty-seven patients scheduled for select laparoscopy cholecystectomy were randomly divided into group A(24 cases) and group B(23 cases).Group A received fentanyl,propofol and vecuronium for induction of anesthesia,group B were induced with fentanyl,thiopental and vecuronium.Anesthesia was maintained by isoflurane inhalation in two groups.Recovery characteristic,the incidence of postoperative nausea and vomiting,and the patient number of antiemetic use were observed for 24h.Results Postoperative awakening time,postoperative awake time,the incidence of postoperative nausea and vomiting,and the patient number of antiemetic use in group A were much lower than those in group B(P<0.05).Conclusion Propofol administered for general anesthesia is effective in preventing postoperative nausea and vomiting,and can shorten the time of anesthetic recovery markedly.

【关键词】 异丙酚麻醉恶心呕吐
【Key words】 Propofol Anesthesia Nausea Vomiting
  • 【文献出处】 中国基层医药 ,Chinese Journal of Primary Medicine Pharmacy , 编辑部邮箱 ,2003年06期
  • 【分类号】R614
  • 【被引频次】3
  • 【下载频次】34
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