【摘要】 目的　探讨脂质 ( Castoroil,C.O)抗血吸虫尾蚴钻肤的效果 ,降低血吸虫病发病率。　方法　分别应用脂质 0 .3ml/只· d给小鼠灌胃和皮肤表面 0 .15 ml/ cm2· d外涂两种不同方法后 ,所有实验小鼠再用日本血吸虫尾蚴 ( 6 0± 2 )条 /只经皮感染 ,40 d后解剖 ,进行成虫计数 ,并与对照组比较。　结果　两组成虫数经 t检验 ,差异有显著性意义。　结论　脂质无论内服或外涂均能明显降低尾蚴钻肤的能力。更多还原

【Abstract】 Objective To explore the preventive effect of Castor oil on the skin penetration by cercaria of Schistosoma japonicum (and to reduce the incidence of the disease). Methods After oral administration(0.3 ml/animal·d) or skin application (0.15 ml/cm2·d) of Castor oil, mice were exposed via skin to cercaria of S. japonicum(60±2). 40 days after the infection, the animals were dissected for number of imago. Results Comparison between experimental group and control group showed a significant difference. Conclusion Castor oil, wheather given orally or curtaneously, can substantially reduce the cercarias ability to penetrate skin.更多还原